Cialis main generic name is Tadalafil. What is it? How does it work? Let’s answer this questions but first of all grapple with the fact what generic medications are?
What are Generic Drugs?
Generic is a medication with proven pharmaceutical and biological equivalence of original drug. That is, a drug having the same composition of active ingredients, dosage form and effectiveness as well as original drug, but having no patent protection.
Generics may differ from a brand drug in additive agents composition. It is placed on the market after original drug expiry of patent protection.
A necessary requirement for sale of generic drugs is proven pharmaceutical, biological and therapeutic equivalence to the original. Generic Cialis has the same quality, composition, and effects but a lower price. Here you can buy generic Cialis online and without prescription.
Do Generics Differ from Branded Drugs?
Differences exist, but they are not so significant. For a visual example, look at the table below.
Difference: Brand vs Generic Medications
| Reference Point | Similarity with Original | More Details |
| Active Substance | yes | Generics manufacturers should constantly supervise their drugs to meet quality standards and to be identical to brand medications. The active substance is the main medication constituent, the active substance of generics is 95% identical to original one. |
| Effect | yes | If an active constituent of generics is the same as in brand drugs, the effect will be identical. |
| Name | no | Generics cannot obtain branded drugs names, because it destroys copyright rights. |
| Form and Pill’s Colour | no | Form and Pill’s Colours are also a property of the pharmaceutical company and cannot be copied. |
| Price | no | Generics price is considerably lower. |
| Composition | yes | Generics composition may differ in some additive agents. |
Why Are Generic Drugs Cheaper than Original Drugs?
The main reason for low prices is their production required much lower expenses. Cost of generics is lower and therefore they are sold at lower price.
Manufacturers of generic drugs are not spent money on:
- research and development of drug;
- obtain a certificate confirming safety and efficacy of medicines;
- lack of advertising and marketing expenses.
Expenses of pharmaceutical companies on research, development, testing, licensing of the drug are very great. In future, this is the reason for branded drugs high cost. Pharmaceutical companies need to repay expenditures and make a profit before the expiry of patent protection.
The Most Popular Generic of Cialis is Tadalafil
Tadalafil is used to treat the following diseases:
- pulmonary hypertension;
- benign prostatic hyperplasia;
- erectile dysfunction.
Disease, for treatment of which Tadalafil was originally intended – pulmonary hypertension. During 16-week trials, scientists have found that compared with placebo group patients treated with 2.5-40 mg of the drug, feel a significant improvement. A recent study showed that this drug really facilitates patient’s condition in case of pulmonary hypertension. However, medicine apparently does not eliminate the risk of death.
Preparations containing tadalafil in its structure, are applied in the treatment of benign prostatic hyperplasia. This disease is characterized by symptoms such as frequent urination, low urine pressure, frequent night-time urination, incomplete emptying of the bladder, and others. However, this substance cannot be combined with alpha-blockers. This can lead to dangerous pressure reduction. The preparation also cannot be combined with nitrate-containing drugs.
Generally, tadalafil is used to treat erectile dysfunction. The drug helps to overcome any degree of impotence. The principle of its action is the same as that of other PDE-5 inhibitors. An important difference is a long-lasting effect. As already mentioned, the effect on women has been insufficiently studied. Therefore, drugs with tadalafil are recommended for men only. You can find reviews of women taking this drug on the Internet. Who took medicine, there were noted some increased sensations.
Application
Tadalafil can be taken daily or one-time. With daily use, 5 mg of the drug is maximum dosage. In this case, it is recommended to avoid missing drug application. The course of treatment for erectile dysfunction is 1 week. The agent can also be used for benign prostatic hyperplasia treatment. This disease is treated within 1 month. Although usually, Tadalafil causes a positive effect after 2 weeks.
You can also take this agent one-time (if necessary). How to take it in this case? Despite the fact that active ingredient tadalafil takes effect within 15-20 minutes, doctors recommend taking a pill for about 45-60 minutes before planned sexual intercourse. This can be done before, during or after meals. Such ED medicines do not become less effective because of fatty food. The medicine can restore this shortcoming.
Dosage
Currently, tadalafil tablets are released in the dosages of 2.5 mg, 5 mg, 10 mg and 20 mg. Tablets 5 mg is used for daily reception and 10 and 20 mg – for a single dose. The dosage of 2.5 mg was approved by FDA later (in 2009). It is used to adjust a daily amount of active ingredient.
Generics
In 2003, FDA approved Tadalafil. Preparations containing this agent can be produced only by a company engaged in its development. A few years later patent ended that protected this agent. India has become the second state, mastered production of the so popular drug. The drug produced in India is called generic. It has absolutely no different from the original drug. The difference is only noticeable in price and name. Tadalafil is several times cheaper. Despite this, they are effective as well as the original drug.
